Nivethitha Nagarajan and Jayachandran Sadaksharam
Ameloblastoma is unicentric, non-functional, intermittent in growth, anatomically benign and clinically persistent tumor of the oral and maxillofacial region. Ameloblastoma is the second most common odontogenic tumor in the oral and maxillofacial region. It represents about 1% of all oral odontogenic epithelial tumors and 11% of all odontogenic tumors. Three groups namely multicystic, unicystic and peripheral are recognized in the clinico-radiological classification. Various non-invasive radiographic analytic methods determine the diagnosis and prognosis of ameloblastoma. Targeted therapy against various genes is a promising therapeutic modality for Ameloblastoma. Hence future research can be directed towards non- invasive or minimally invasive diagnostic techniques and targeted therapies.