Shagun Sharma
The first reported case of COVID-19 was in Wuhan, China in December 2019 after which it spread all around the world and was declared a pandemic by WHO on March 11, 2020. As the pandemic progressed, the scientific community was faced with the challenge of diagnosing, treating, and isolating the infected patients. Asymptomatic carriers and false-negative results were a few of the major challenges which revealed the shortcomings of detection techniques. Now, in series of constant strive researchers are working to develop advanced techniques, nano-particles (NPs) based biosensing approaches can be a hope offering novel diagnosis meeting the current demand of rapid and early detection of COVID-19 cases. Gold NPs, lanthanide-doped NPs, oxides of carbon, and graphene NPs in combination with amperometric, calorimetric, and fluorescence techniques are in practice for SARS-CoV-2 biosensing. Pyrediyne a non-toxic carbon based nano-particles (NPs) with enhanced electronic properties and 25% progressive photoluminescence quantum yield could set up standards for detection of SARS-CoV-2. Effortless and cost-efficient preparation of pyrediyne quantum dots (PQD) will be carried out via the soxhlet extraction method.