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Artículo de investigación

Region Specific Effects of Aging and the Nurr1-Null Heterozygous Genotype on Dopamine Neurotransmission

Evangel Kummari, Shirley Guo-Ross and Jeffrey B Eells

The transcription factor Nurr1 is essential for dopamine neuron differentiation and is important in maintaining dopamine synthesis and neurotransmission in the adult. Reduced Nu..Ver más»

Artículo de revisión

A Review on Drug Combination Strategy for Pharma Life Cycle Management

Prashanth R Rikkala, Sidharth Shankar Jha, Debasis Pore, Krishna Madhuri Manda, Nandu Gattu, Sanjeev Kumar Shangary*

Discovering a new drug and developing it to the clinic is a, time-consuming and expensive process. A successfully developed patented drug enjoys market exclusivity which provide..Ver más»

Mini revisión

Cognitive Decline in Older Multiple Sclerosis Patients

Jin Yong

This narrative review focuses on several significant issues involving cognitive ageing and dementia in older adults with multiple sclerosis (PwMS): Are elderly MS patients more ..Ver más»

Investigación

Covid-19 Pandemic: A Systematic Review of Nigeria Situation from the Global Perspective between February to June 2020 of the Outbreak

Onyechi Nwankwo, Nkiru E. Obande-Ogbuinya, Ben N. Ohuruogu, Uzochukwu C. Ibe, Theresa N. Nnaji, Ifeyinwa M. Okafor, Akamu L. Nworie, Stanly C. Anyigor- Ogah, Chinedu Nweke Idakari, John Donald Nweze, OkochaYusuf Item, Christian O. Aleke

COVID-19 Pandemic remains a source of worry to many Nigerians since it's manifestation in the country on 28th February 2020. This common enemy was first identified in Wuhan ..Ver más»

Comunicación breve

From the Interaction of Neurotoxic Peptides and Proteins with the Cys-loop Receptors to Novel Drugs

V.Tsetlin

The talk is devoted to research on neurotoxic proteins and peptides carried out at our Institute in collaboration with leading Russian and foreign laboratories. It focuses on to..Ver más»